Dr. Lerman graduated from the Technion medical school and completed his training in internal medicine and cardiology at the Mayo Clinic.

Dr. Lerman is a Professor of Medicine and the chair for research of the cardiovascular division at the mayo clinic and the Director of the center for coronary physiology and Imaging. His research program is focused on detection, prevention and treatment of early coronary atherosclerosis and acute coronary syndrome in humans. The program has an emphasis on novel technologies, invasive and non-invasive assessment of coronary artery disease, imaging of the vulnerable plaque, novel risk factors and vascular injury in repair. The NIH, AHA and the Department of Defense fund his research program.